This is a fascinating piece of work. It will be interesting to see if similar processes occur in some of the common diseases with such deposits, for example Alzheimer’s and Parkinson’s disease. Furthermore, if this is the case, can modulating this same pathway be a route to new therapeutic approaches in these more prevalent conditions that afflict many millions of sufferers around the world? Ultimately only more research will tell us this.
Dr Eric Karran, the director of research at Alzheimer’s Research UK, added the usual cautionary note:
The findings present the appealing concept that one treatment could have benefits for a range of different diseases; however the idea is in its early stages. The research focuses on the effects of the prion protein and we would need to see the same results confirmed in Alzheimer’s and Parkinson’s to really strengthen the evidence.